Highlights
- Lactium® provides milk protein hydrolysate to temporarily help reduce symptoms of mild mental and physical stress
Indications
- Temporarily reduces symptoms of mild mental and physical stress
Description
Sereniten Plus contains milk protein hydrolysate, which temporarily helps reduce symptoms of mild mental and physical stress. The milk protein hydrolysate, in the form of Lactium®, contains a bioactive decapeptide that has been clinically studied for reducing stress. During times of physical or mental stress, cortisol levels in the body rise as a defensive mechanism to protect the body. Although this is an adaptive mechanism, prolonged secretion of cortisol can have negative impacts on proper functioning, including reduced immune function and poor digestion. In participants subject to induced stress, one randomized control study found that alpha S1-casein hydrolysate, the active peptide of Lactium, decreased plasma cortisol levels, and lowered heart rate compared to controls. Another study found that alpha S1-casein hydrolysate also improved feelings of well-being and digestion among stressed women.
Sereniten Plus also contains L-theanine and vitamin D. Vitamin D is a factor in sustaining good health and helps in the maintenance of bones and teeth.
Functions
The neurochemical and hormonal reactions to stress are regulated through the Hypothalamic-Pituitary-Adrenal axis (HPA axis), which is designed for acute stressors that resolve rapidly. Present day chronic, low-grade stress results in the continual release of CRH (Corticotrophin Releasing Hormone) from the hypothalamus. This chronic secretion causes dysfunction in the HPA axis, desensitizing the hypothalamic and pituitary receptors to negative feedback from adrenaline, noradrenalin, and, in particular, cortisol. Loss of negative feedback within the neuro-hormonal system can result in a multitude of health issues. When the negative feedback loop within the HPA-axis is disrupted, chronic hormonal secretion becomes “normal.” In this state, people either fail to recognize they are stressed, or may experience an exaggerated emotional and physical response to every stressor, including intolerance to noise or light, or feeling overwhelmed by simple tasks. Stress affects so many aspects of health that it is becoming crucial to rebalancing the HPA-axis. Lactium®, a bioactive milk protein hydrolysate isolated from cow’s milk, helps to temporarily reduce symptoms of mild mental and physical stress by mediating three areas of the HPA-axis.
Studies involving humans using alpha-S1-casein tryptic hydrolysate, the active peptide of Lactium®, have indicated calming effects. In participants subject to induced stress, one randomized control study found that alpha S1-casein hydrolysate, the active peptide of Lactium, decreased plasma cortisol levels, and lowered heart rate compared to controls. Another study found that alpha S1-casein hydrolysate also improved feelings of well-being and digestion among stressed women.
Sereniten Plus also contains L-theanine and vitamin D. L-Theanine is a unique amino acid originally found in green tea, while vitamin D helps maintain good health and supports bone health.