In addition to its role in memory and cognitive function, preclinical research suggests that Bacopa monnieri maintains healthy enzyme activity in the brain, contributing to the body’s response to stress. A double-blind crossover trial indicated that rhodiola may play a role in reducing mild fatigue in stressful conditions. In a separate double-blind, placebo-controlled pilot study, rhodiola was shown to influence both physical and mental stress in students. Similarly, the amino acid L-tyrosine has been studied for its potential to aid cognitive function and memory under stress.
Eleutherococcus senticosus (eleuthero) is classified as an adaptogen and has been traditionally used to enhance adrenal function and stress resilience. Like ashwagandha, it has been valued for its role in promoting energy, vitality, and immune function. Chamomile and lemon balm have long been recognized for their calming properties.
B vitamins and magnesium help counteract the effects of stress on nutrient balance. B-complex vitamins have been associated with neurotransmitter function and energy metabolism. Vitamin B5 is particularly important in maintaining adrenal gland function, contributing to the body's ability to handle stress. Vitamin C plays a role in neutralizing free radicals produced during the stress response.
