NPN 80095838, NPN 80095839
Highlights
HappySense® naturally enhances serotonin levels. Now with our timed-release caplets, they help deliver 5-HTP gradually, helping to smooth out the fluctuations in serotonin levels that can occur with immediate-release forms.
- Helps promote healthy mood balance
- Helps relieve symptoms of fibromyalgia
- Used as a sleep aid
- Reduces carbohydrate cravings
- Helps reduce the severity and duration of migraine headaches when taken as a preventative
- Available in 50 mg and 100 mg
Overview
HappySense 5-HTP naturally enhances serotonin levels, which in turn helps promote healthy mood balance, relieve symptoms of fibromyalgia, and reduce the severity and duration of migraine headaches when taken as a preventative. 5-HTP can also be used as a sleep aid.
With a program of reduced intake of dietary calories and increased physical activity, 5-HTP can help in weight management by reducing carbohydrate cravings.
Recommended adult dose – 50 mg
Healthy mood balance: 1–2 caplets 3 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Use for at least 1 week to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Relief of symptoms of fibromyalgia: 2 caplets 3–4 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg, 2–3 times daily, and slowly increase to effective dose over a period of 2 weeks. Use for at least 2 weeks to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Migraine prophylaxis: 2 caplets 2–3 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg, 2–3 times daily, and slowly increase to effective dose over a period of 2 weeks. Use for at least 2–3 weeks to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Weight management: 5 caplets 3 times daily or as directed by a health care practitioner. Take 30 minutes prior to a meal. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Consult a health care practitioner for use beyond 12 weeks.
Sleep aid: 2–4 caplets daily with food or as directed by a health care practitioner. Take 30–45 minutes before bedtime.
Recommended adult dose – 100 mg
Healthy mood balance: 1 caplet 3 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Use for at least 1 week to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Relief of symptoms of fibromyalgia: 1 caplet 3–4 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Use for at least 2 weeks to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Migraine prophylaxis: 1 caplet 2–3 times daily with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Use for at least 2–3 weeks to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Weight management: 3 caplets 3 times daily or as directed by a health care practitioner. Take 30 minutes prior to a meal. To minimize the risk of gastrointestinal side effects, start dosing at 100 mg 2–3 times daily and slowly increase to effective dose over a period of 2 weeks. Consult a health care practitioner for use beyond 12 weeks.
Sleep aid: 1–2 caplets daily with food or as directed by a health care practitioner. Take 30–45 minutes before bedtime.
Nutrition
Each Caplet Contains
Medicinal Ingredients:
| L-5-HTP (L-5-hydroxytryptophan) (Griffonia simplicifolia) (seed) | 50 mg / 100 mg |
Non-medicinal Ingredients:
Microcrystalline cellulose, dicalcium phosphate, carbohydrate gum (cellulose), coating (carbohydrate gum [cellulose], glycerin), vegetable grade magnesium stearate (lubricant).
Studies
- cross-over study with L-5-hydroxytryptophan versus placebo. Clinical Journal of Pain, 2(2), 123-30.
- Birdsall, T.C. (1998). 5-Hydroxytryptophan: A clinically-effective serotonin precursor. Alternative Medicine Review, 3(4), 271-280.
- Ceci, F., Cangiano, C., Cairella, M., et al. (1989). The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. Journal of Neural Transmission, 76(2), 109-117.
- Jacobsen, J.P.R., Oh, A., Bangle, R., et al. (2019). Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proofof-concept. Neuropsychopharmacology, 44(12), 2082-2090.
- Jangid, P., Malik, P., Singh, P., et al. (2013). Comparative study of efficacy of L-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian Journal of Psychiatry, 6(1), 29-34.
- Javelle, F., Lampit, A., Bloch, W., et al. (2020). Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis. Nutrition Reviews, 78(1), 77-88.
- Sarzi, P.P., & Caruso, I. (1992). Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. Journal of International Medical Research, 20(2), 182-189.
- Shaw, K., Turner, J., & Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression (Review). Cochrane Database Systematic Reviews, (1), CD003198.
- Wyatt, R.J., Zarcone, V., Engelman, K., et al. (1971). Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalography and Clinical Neurophysiology, 30(6), 505-509.